01 Jun Dr Sudeshen Naidoo: Prostate Cancer. Should you screen?
According to the latest National Cancer Registry (NCR 2012), the number of cases diagnosed in that year was 6807.
The estimated life time risk is 1:19 and makes-up 18,45% of all cancers diagnosed,” said specialist radiation oncologist, Sudeshen Naidoo. The median age of diagnosis is 70 years, but with increased screening, more younger men are being diagnosed. The prostate gland consists of the peripheral zone (70% of glandular prostate and site of nearly all cancers), the central zone (25% of the glandular prostate), the transition zone (surrounding the urethra and the site of benign prostatic hypertrophy), and the anterior fibromuscular stroma. “Approximately 50-80% of tumours involve the prostate apex, and around 85% of patients have multifocal disease in the prostate. More than 95% of prostate cancers are adenocarcinomas,” said Naidoo. Potential risk factors » Advanced age » Benign prostatic hypertrophy » Diet e.g. high-fat intake » Family history of prostate cancer – frequency of prostate cancer, increases with family history of first degree relatives with prostate cancer. » Hormonal factors e.g serum testosterone and androgens are required for the development of prostate cancer » Race /ethnicity e.g Black.